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Published on: February 21, 2011
A knowledge gap unmasked: viral transmission in surgical smoke: a systematic review
Connal Robertson-More1, Ted Wu2
1Department of Surgery, North Island Hospital, Vancouver Island Health Authority, 375 2 Ave, Campbell River, BC, V9W 3V1, Canada. crobertsonmore@yahoo.com.
Background:
Concerns regarding the aerosolized transmission of SARS-CoV-2 via SS have caused significant apprehension among surgeons related to the use of minimally invasive surgery (MIS) during the COVID19 pandemic. While a limited number of studies have previously demonstrated the presence of viral material in SS, no comprehensive systematic review exists on the subject of viral transmission in SS. Methods A systematic review of the literature was conducted as per PRISMA guidelines. MEDLINE, EMBASE, and CENTRAL databases were searched for publications reporting the primary outcome of the presence of viral particles in SS and secondary outcomes of indices suggesting transmission of viable virus particles in SS producing clinically important infection. All human, animal, and in vitro studies which used accepted analytic techniques for viral detection were included. A meta-analysis was not complete due to methodologic heterogeneity and inconsistent reporting of outcomes of interest.
Results:
23 publications addressed the presence of viral components in SS, and 19 (83%) found the presence of viral particles in SS. 21 publications additionally studied the ability of SS to induce clinically relevant infection in host cells, with 9 (43%) demonstrating potential for viral transmission.
Conclusion:
Evidence exists for viral transmission via SS. However, HPV remains the only virus with documented transmission to humans via SS. While meaningful translation into practical guidelines during the COVID pandemic remains challenging, no evidence exists to suggest increased risk in MIS.
Insights
Surgical smoke (SS) may contain viral particles, raising concerns during the COVID-19 pandemic. While evidence suggests viral transmission via SS, current data does not indicate an increased risk in minimally invasive surgery (MIS).
Area of Science:
- Virology
- Surgical Safety
- Infectious Disease Transmission
Background:
- Surgeons express apprehension regarding aerosolized SARS-CoV-2 transmission via surgical smoke (SS) during the COVID-19 pandemic.
- Limited studies indicate viral material in SS, but a comprehensive systematic review on viral transmission in SS is lacking.
Purpose of the Study:
- To systematically review the literature on the presence of viral particles in surgical smoke.
- To assess the potential for viable virus particle transmission from surgical smoke leading to clinically significant infection.
Main Methods:
- A systematic literature review adhering to PRISMA guidelines.
- Searched MEDLINE, EMBASE, and CENTRAL databases for relevant human, animal, and in vitro studies.
- Focused on primary outcomes of viral particle presence in SS and secondary outcomes of transmission potential.
Main Results:
- Nineteen of 23 publications (83%) detected viral particles in surgical smoke.
- Nine of 21 publications (43%) demonstrated the potential for viral transmission from surgical smoke to induce clinically relevant infections.
Conclusions:
- Evidence supports the potential for viral transmission via surgical smoke.
- Human Papillomavirus (HPV) is the only virus documented for transmission to humans through SS.
- No evidence suggests an increased risk associated with minimally invasive surgery (MIS) despite challenges in translating findings into practical COVID-19 pandemic guidelines.
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