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Atrial high-rate episodes: a comprehensive review
Gelu Simu1, Radu Rosu1, Gabriel Cismaru1
1Department of Internal Medicine, Cardiology-Rehabilitation, 'Iuliu Haţieganu' University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Insights
Atrial high-rate episodes (AHRE), detected by cardiac devices, are linked to stroke risk but are less severe than atrial fibrillation (AF). Their management remains challenging due to limited evidence.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Cardiac electronic implantable devices (CIEDs) detect atrial high-rate episodes (AHRE), a distinct arrhythmic entity.
- AHRE are atrial tachyarrhythmias, often considered precursors to atrial fibrillation (AF), but can also represent other supraventricular arrhythmias.
- While CIED-detected AHRE correlate with increased stroke risk, this risk is substantially lower than that of clinical AF.
Purpose of the Study:
- To review the epidemiology, predictive factors, clinical impact, and management strategies for AHRE.
- To address the challenges in managing AHRE due to current evidence gaps.
Main Methods:
- Literature review focusing on CIED-detected AHRE.
- Analysis of epidemiological data, risk factors, and clinical outcomes.
- Evaluation of current and proposed management guidelines.
Main Results:
- AHRE are increasingly recognized due to CIED monitoring capabilities.
- A temporal correlation between AHRE and thromboembolic events appears lacking.
- The clinical significance and optimal management of AHRE require further investigation.
Conclusions:
- AHRE represent a complex arrhythmia entity requiring careful consideration in clinical practice.
- Further research is essential to clarify the prognostic implications and refine management protocols for AHRE.
- Understanding AHRE is crucial for optimizing patient care and device management.
Abstract:
Cardiac electronic implantable devices (CIEDs) have the ability to monitor, store and interpret complex arrhythmias, which has generated a new arrhythmic entity: atrial high-rate episodes (AHRE). AHRE are atrial tachyarrhythmias, detected only by CIEDs. They are widely considered a precursor to atrial fibrillation (AF) but can also be represented by other kinds of supraventricular arrhythmias such as atrial flutter or atrial tachycardia. CIED-detected AHRE are associated with an increased risk of stroke, but the risk is significantly lower than the stroke risk of clinical AF. Moreover, there seems to be no temporal correlation between AHRE and thromboembolic events. Because of the current gaps in evidence, the appropriate management of this arrythmia can be challenging. In this review we take into account the epidemiology behind AHRE, predictive factors, clinical impact and management of this arrhythmia.
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