Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An iterative phase correction program for nuclear magnetic resonance (NMR) spectra.

C N Chen1, L S Kan

  • 1Biomedical Engineering and Instrumentation Branch, National Institutes of Health, Bethesda, MD 20892.

Computer Methods and Programs in Biomedicine
|January 1, 1988
PubMed
Summary

This study introduces an iterative algorithm to automatically correct phase errors in Nuclear Magnetic Resonance (NMR) spectroscopy. The method optimizes spectral parameters without prior error knowledge, maximizing the area ratio above and below the spectrum for accurate phasing.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Clinicopathological and molecular genetic features of Crohn's disease].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2024
Same author

[Bronchiolar adenoma: a clinicopathological analysis of 15 cases].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2020
Same author

[Monomorphic epitheliotropic intestinal T-cell lymphoma: a clinicopathological analysis of twelve cases].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2020
Same author

[Advances in the research of gastroenteropancreatic neuroendocrine tumors].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2019
Same author

[Role of cytokines in the pathogenesis of inflammation bowel disease].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2019
Same author

First co-infection case of melioidosis and Japanese encephalitis in China.

BMC infectious diseases·2018

Area of Science:

  • Analytical Chemistry
  • Spectroscopy
  • Computational Chemistry

Background:

  • Phase errors in Nuclear Magnetic Resonance (NMR) spectroscopy can distort spectral data.
  • Accurate spectral phasing is crucial for reliable data interpretation and quantitative analysis.
  • Manual phase correction can be subjective and time-consuming.

Purpose of the Study:

  • To develop an automated, iterative algorithm for correcting zeroth and first-order phase errors in NMR spectra.
  • To provide a computational tool (FORTRAN program) for implementing the phase correction algorithm.
  • To validate the algorithm's performance through sample runs without requiring prior knowledge of phase errors.

Main Methods:

  • An iterative algorithm was designed to optimize spectral parameters.

Related Experiment Videos

  • The algorithm assumes maximum ratio of spectral area above to below the baseline for correct phasing.
  • A FORTRAN computer program was developed and is provided.

    • Main Results:

    • The iterative algorithm effectively corrects zeroth and first-order phase errors.
    • Two sample runs demonstrated the algorithm's practical application and efficacy.
    • The method does not require a priori knowledge of the phase errors present in the NMR spectra.

    Conclusions:

    • The developed iterative algorithm provides an objective and automated approach to NMR spectral phasing.
    • The FORTRAN program facilitates the implementation of this phase correction technique.
    • This method enhances the accuracy and reliability of NMR spectroscopic data analysis.