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[Research advances on the application of fetal dermal mesenchymal stem cells in burn wound treatment]

Y Pan1, D Y Jiang2

  • 1Department of Rehabilitation Medicine, the Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, China.

Zhonghua Shao Shang Za Zhi = Zhonghua Shaoshang Zazhi = Chinese Journal of Burns
|January 27, 2021
PubMed

Fetal dermal mesenchymal stem cells (FDMSCs) are pluripotent stem cells derived from skin tissue of accidentally aborted fetuses of healthy pregnant women who are free of genetic diseases and do not take abortion drug. FDMSCs have exosome secretion activity, high proliferation and self-renewal abilities, low immunogenicity, and advantages of homing to damaged tissue and promoting tissue regeneration. In recent years, studies on basic biological characteristics, capacity of inducing differentiation in vitro, and promotion of skin wound repair provide new direction for the clinical treatment of burn patients in the future. In this review, we summarize the research advances of FDMSCs in promoting burn wound healing.

Keywords:
BurnsFetal dermal mesenchymal stem cellsWound healing

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