Related Experiment Video
Updated: Nov 19, 2025

08:03
In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
2.6K
Difficulties in diagnosing vertebral osteomyelitis in a child
Jonathan Holzmann1, Sunday Pam2,3, Geoffrey Clark4
1Paediatrics, Queensland Health, Brisbane, Queensland, Australia jonathan.holzmann@health.qld.gov.au.
BMJ Case Reports
|January 27, 2021
Summary
Pediatric vertebral osteomyelitis diagnosis can be delayed. This case highlights how bone scans and further MRI confirmed infection despite initial negative imaging, emphasizing clinical suspicion.
Area of Science:
- Pediatric infectious diseases
- Musculoskeletal imaging
- Diagnostic challenges in pediatrics
Background:
- Vertebral osteomyelitis is uncommon in children, often leading to delayed diagnosis.
- Early recognition is crucial for effective treatment and preventing complications.
Observation:
- A child presented with fever, back pain, and elevated C-reactive protein, indicating Staphylococcus aureus bacteremia.
- Initial CT, MRI, and ultrasound scans did not reveal vertebral osteomyelitis or the source of bacteremia.
Findings:
- A bone scan detected increased metabolic activity in the 12th thoracic vertebra (T12).
- A subsequent focused MRI of T12 confirmed the diagnosis of vertebral osteomyelitis.
Implications:
- This case underscores the diagnostic difficulties in pediatric vertebral osteomyelitis.
- Clinicians must maintain clinical suspicion and utilize further investigations when initial imaging is inconclusive to ensure timely diagnosis.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
139
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
139
Bone Disorders
4.8K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
4.8K