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Updated: Nov 19, 2025

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Published on: January 12, 2022
Etiology of Uveitis in Upper Egypt
Eiman Abd El Latif1, Asaad Nooreldin2, Mohammed Shikhoun Ahmed3
1Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Tuberculosis and sarcoidosis are the leading causes of uveitis in Upper Egypt. This study reviewed 982 patients, finding anterior uveitis most common, with challenges in diagnosing pediatric cases.
Area of Science:
- Ophthalmology
- Immunology
- Public Health
Background:
- Uveitis, a significant cause of vision loss, requires understanding regional etiological patterns.
- Ocular inflammation presents diverse challenges in diagnosis and management.
Purpose of the Study:
- To identify and report the primary causes of uveitis in Upper Egypt.
- To analyze the demographic and clinical characteristics of uveitis patients in a referral setting.
Main Methods:
- Retrospective review of medical charts for uveitis cases.
- Data collected from January 2015 to January 2020 at a referral ocular inflammation clinic.
- Inclusion of 982 patients diagnosed with uveitis.
Main Results:
- Anterior uveitis (34.4%) was the most frequent type, followed by posterior uveitis (25.6%).
- Bilateral uveitis occurred in 51.7% of patients.
- In patients under 18, juvenile idiopathic arthritis was common, but etiology remained undetermined in a quarter.
Conclusions:
- Tuberculosis and sarcoidosis were identified as the most prevalent causes of uveitis in this Upper Egyptian cohort.
- Understanding regional etiologies is crucial for targeted uveitis management.
- Diagnostic challenges persist, particularly in pediatric uveitis cases.
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