Related Experiment Video
Updated: Nov 19, 2025
08:36
Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
Published on: April 19, 2024
890
An update on Heck's disease-a systematic review.
Sneha Sethi1, Anna Ali2, Xiangqun Ju1
1Australian Research Centre for Population Oral Health, Adelaide Dental School, University of Adelaide, Adelaide, Australia.
Journal of Public Health (Oxford, England)
|January 27, 2021
Summary
This review of Heck's disease found a mean age of 23.1 years and a 3:4 male to female ratio, with higher incidence noted in Europe. Further research is needed to understand its transmission patterns.
Area of Science:
- Dermatology
- Epidemiology
- Genetics
Background:
- Heck's disease (also known as focal epithelial hyperplasia) has a suspected genetic and familial inheritance pattern.
- Previous research suggests ethnic associations, but a comprehensive systematic review was lacking.
Purpose of the Study:
- To update age and gender predilections for Heck's disease.
- To investigate the proposed links between Heck's disease and ethnic/geographical factors.
Main Methods:
- A systematic review of Heck's disease case reports from 1966 to the present.
- Inclusion of 95 case reports after duplicate removal and adherence to STROBE guidelines for quality assessment.
Main Results:
- The age range observed was 3-92 years, with a mean age of 23.1 years.
- A male to female ratio of 3:4 was identified.
- Increased incidence of Heck's disease was observed in the European region.
Conclusions:
- Heck's disease shows a higher prevalence in indigenous populations globally.
- Further research is recommended to elucidate the transmission and spread patterns of Heck's disease.
Related Concept Videos
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
225
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
225
01:23Rheumatic Heart Disease I: Introduction
186
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
186
01:24Chronic Kidney Disease II: Clinical Manifestations
339
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
339
01:20Rheumatic Heart Disease IV: Nursing Management
126
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
126
01:26Nephrotic Syndrome II : Assessment and Medical Management
73
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
73
01:21Rheumatic Heart Disease III: Medical Management
125
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
125