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Updated: Nov 19, 2025

Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies
Published on: August 11, 2023
Biomedical applications of vibrational spectroscopy: Oral cancer diagnostics
Hugh J Byrne1, Isha Behl2, Genecy Calado2
1FOCAS Research Institute, Technological University Dublin, City Campus, Dublin 8, Ireland.
Abstract:
Vibrational spectroscopy, based on either infrared absorption or Raman scattering, has attracted increasing attention for biomedical applications. Proof of concept explorations for diagnosis of oral potentially malignant disorders and cancer are reviewed, and recent advances critically appraised. Specific examples of applications of Raman microspectroscopy for analysis of histological, cytological and saliva samples are presented for illustrative purposes, and the future prospects, ultimately for routine, chairside in vivo screening are discussed.
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