Related Experiment Video

Updated: Nov 19, 2025

Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.3K

Midterm outcome of off-pump CABG for severe LV dysfunction-Does LV size and function predict their midterm outcome?

Chandrasekaran Ananthanarayanan1, Kartik Patel1, Vivek Wadhawa1

  • 1Department of CVTS, U. N. Mehta Institute of Cardiology and Research Center (affiliated to BJ Medical College, Ahmedabad), Ahmedabad, Gujarat, India.

Journal of Cardiac Surgery
|January 27, 2021
PubMed

Insights

Off-pump coronary artery bypass grafting (OP-CABG) offers good midterm outcomes for severe left ventricular dysfunction. Postoperative left ventricular ejection fraction and dimensions predict midterm mortality in these high-risk patients.

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Surgery
  • Cardiology

Background:

  • Surgical revascularization is superior for ischemic cardiomyopathy.
  • Off-pump coronary artery bypass grafting (OP-CABG) is a safe revascularization method for high-risk patients.
  • Limited data exists on postoperative ventricular function and size impact on midterm outcomes.

Purpose of the Study:

  • To evaluate the midterm outcomes of OP-CABG in patients with severe left ventricular (LV) dysfunction.
  • To identify predictors of operative and midterm mortality in this patient cohort.

Main Methods:

  • Retrospective analysis of 211 consecutive patients undergoing OP-CABG from January 2017 to December 2018.
  • Statistical analysis of operative and midterm outcomes, including mortality and major adverse cardiovascular events.
  • Assessment of postoperative left ventricular ejection fraction (LVEF) and dimensions as predictors.

Main Results:

  • Operative mortality was 10.9%, with preoperative NYHA class and postoperative IABP insertion as independent predictors.
  • Midterm cardiac mortality was 5.8% over a mean follow-up of 3.14 years.
  • Postoperative LVEF and LV dimensions were independent predictors of midterm mortality; 89% midterm MACE-free survival.

Conclusions:

  • OP-CABG can achieve complete revascularization in severe LV dysfunction patients with good midterm results.
  • High early operative mortality is noted, but postoperative LV function and dimensions are key predictors of midterm survival.
Abstract

Keywords:
LV dimensionsLV dysfunctionoff-pump CABG

More Related Videos

Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs08:19

Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs

Published on: July 12, 2022

3.1K
Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice08:21

Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice

Published on: June 15, 2020

4.6K

Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
126
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
148
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
148
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
124