Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Blue Emissive Heavy Atom-Free Multiresonant Thermally Activated Delayed Fluorescent Emitter Shows Ultra-Fast Reverse Intersystem Crossing.

Angewandte Chemie (International ed. in English)·2026
Same author

Organic light-emitting diode-based photodynamic therapy treats bacterial infection in a preclinical <i>ex vivo</i> burn wound model.

Burns & trauma·2026
Same author

Interaction of Polymer of Intrinsic Microporosity PIM‑1 with Explosive Analytes at the Molecular Level: Combined Experiment and Computational Modeling.

The journal of physical chemistry. C, Nanomaterials and interfaces·2026
Same author

Corrigendum to "Photodynamic therapy offers a novel approach to managing miltefosine-resistant cutaneous leishmaniasis" [Biomed. Pharmacother. 177 (2024) 116881].

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
Same author

Mapping the evidence on lifestyle diseases: protocol for a systematic scoping review.

Systematic reviews·2026
Same author

Novel 4,8-benzobisthiazole copolymers and their field-effect transistor and photovoltaic applications.

Journal of materials chemistry. C·2026

Related Experiment Video

Updated: Nov 19, 2025

Plasmonic Photothermal Cancer Therapy: Nanoparticle-embedded Tumor-tissue-mimicking Phantoms for Visualizing Photothermal Temperature Distribution
06:42

Plasmonic Photothermal Cancer Therapy: Nanoparticle-embedded Tumor-tissue-mimicking Phantoms for Visualizing Photothermal Temperature Distribution

Published on: May 9, 2025

862

Biogenic Gold Nanoparticles Decrease Methylene Blue Photobleaching and Enhance Antimicrobial Photodynamic Therapy.

Irena Maliszewska1, Ewelina Wanarska1, Alex C Thompson2

  • 1Department of Organic and Medicinal Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.

Molecules (Basel, Switzerland)
|January 28, 2021
PubMed
Summary

Gold nanoparticles synthesized by Mucor plumbeus show promise for antimicrobial photodynamic therapy (PDT). These biogenic nanoparticles enhance methylene blue

Keywords:
LEDantibacterial PDTantibiotic resistancebiogenic gold nanoparticlesmethylene blue

More Related Videos

Inactivation of Pathogens via Visible-Light Photolysis of Riboflavin-5&#8242;-Phosphate
08:25

Inactivation of Pathogens via Visible-Light Photolysis of Riboflavin-5′-Phosphate

Published on: April 6, 2022

2.1K
The Synergistic Effect of Visible Light and Gentamycin on Pseudomona aeruginosa Microorganisms
05:57

The Synergistic Effect of Visible Light and Gentamycin on Pseudomona aeruginosa Microorganisms

Published on: July 2, 2013

13.6K

Related Experiment Videos

Last Updated: Nov 19, 2025

Plasmonic Photothermal Cancer Therapy: Nanoparticle-embedded Tumor-tissue-mimicking Phantoms for Visualizing Photothermal Temperature Distribution
06:42

Plasmonic Photothermal Cancer Therapy: Nanoparticle-embedded Tumor-tissue-mimicking Phantoms for Visualizing Photothermal Temperature Distribution

Published on: May 9, 2025

862
Inactivation of Pathogens via Visible-Light Photolysis of Riboflavin-5&#8242;-Phosphate
08:25

Inactivation of Pathogens via Visible-Light Photolysis of Riboflavin-5′-Phosphate

Published on: April 6, 2022

2.1K
The Synergistic Effect of Visible Light and Gentamycin on Pseudomona aeruginosa Microorganisms
05:57

The Synergistic Effect of Visible Light and Gentamycin on Pseudomona aeruginosa Microorganisms

Published on: July 2, 2013

13.6K

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Microbiology

Background:

  • Antibiotic resistance is a significant global health threat.
  • There is an urgent need for novel antibacterial strategies.
  • Antimicrobial photodynamic therapy (PDT) is a promising alternative.

Purpose of the Study:

  • To investigate the potential of gold nanoparticles synthesized by Mucor plumbeus as a medium for PDT.
  • To evaluate the efficacy of these biogenic nanoparticles in combination with methylene blue against bacteria.

Main Methods:

  • Synthesis of gold nanoparticles using Mucor plumbeus mycelium.
  • Characterization of nanoparticle size, shape, and plasmonic properties.
  • Application of PDT using LED light, methylene blue, and biogenic gold nanoparticles against Staphylococcus aureus and Escherichia coli.

Main Results:

  • Spherical gold nanoparticles with uniform distribution and an average size of 17 ± 4 nm were synthesized.
  • The biogenic gold nanoparticles enhanced the photodynamic activity of methylene blue.
  • Effective killing of both Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria was achieved using a simple LED light source.

Conclusions:

  • Biogenic gold nanoparticles synthesized by Mucor plumbeus are effective in enhancing antimicrobial PDT.
  • These nanoparticles prevent photobleaching of methylene blue, improving its bactericidal effect.
  • This approach offers a novel and potentially potent strategy for combating bacterial infections.