Related Experiment Video

Updated: Nov 19, 2025

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
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Heart failure in an elderly man: where is that coronary?

Charlie J Sang1, Stephen A Clarkson2, Elizabeth A Jackson2

  • 1Internal Medicine - Pediatrics Residency Program, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA.

Cardiology in the Young
|January 28, 2021
PubMed

Insights

An unusual coronary artery defect originating from the pulmonary artery can cause heart failure in adults. This case highlights its complex pathophysiology and management with guideline-directed medical therapy.

Area of Science:

  • Cardiology
  • Congenital Heart Disease
  • Adult Cardiology

Background:

  • Anomalous coronary arteries originating from the pulmonary artery (ACAPA) are rare congenital heart anomalies.
  • These anomalies can lead to significant cardiovascular complications, including heart failure, particularly in the adult population.

Observation:

  • This case report details an adult patient presenting with heart failure due to an anomalous right coronary artery originating from the pulmonary artery.
  • The presentation was unusual, underscoring the varied clinical manifestations of ACAPA.

Findings:

  • The study discusses the intricate pathophysiology underlying heart failure in patients with ACAPA.
  • It emphasizes the importance of understanding the hemodynamic consequences of this anomaly.

Implications:

  • Guideline-directed medical therapy plays a crucial role in managing patients with ACAPA and associated heart failure.
  • This case contributes to the understanding and clinical management of rare coronary artery anomalies.

Keywords:
CHDCoronary vessel anomalycardiomyopathy

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