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Cervical spine multiple myeloma and isolated radiotherapy
Diogo Belo1, José Hipólito Reis1, Joaquim Cruz Teixeira2
1Neurosurgery Department, Centro Hospitalar Lisboa Norte (CHLN), Lisbon, Portugal.
Journal of Surgical Case Reports
|January 28, 2021
Summary
Radiotherapy can effectively treat destructive multiple myeloma (MM) spinal lesions, halting progression and promoting bone healing. This approach offers a viable alternative to surgery for select patients with cervical spine involvement.
Area of Science:
- Oncology
- Hematology
- Radiology
Background:
- Multiple myeloma (MM) commonly causes osteolytic spinal lesions.
- Spinal involvement in MM can lead to instability and neurological compromise.
- Current treatment paradigms often involve surgical intervention for spinal lesions.
Observation:
- A case of extensively destructive cervical spine osteolytic lesion due to MM is presented.
- The patient was treated exclusively with radiotherapy.
- Imaging studies (CT and MRI) were used to monitor treatment response.
Findings:
- Radiotherapy arrested the progression of spinal instability.
- The osteolytic lesion showed resolution with evidence of new bone formation.
- Isolated radiotherapy demonstrated efficacy in managing the MM spinal lesion.
Implications:
- Radiotherapy can be a successful standalone treatment for select MM spinal lesions.
- This approach may preserve structural integrity and avoid surgical risks.
- Consideration of radiotherapy as an alternative to surgery in specific MM cases is warranted.
