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New Onset Granulomatosis with Polyangiitis Associated with COVID-19
Moshe Y Bressler1,2, Naeha Pathak2, Kelly Cervellione3
1New York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY, USA.
Case Reports in Dermatological Medicine
|January 28, 2021
Summary
This report details the first case of new-onset Granulomatosis with polyangiitis (GPA) in a patient with active COVID-19. Early immunosuppression is vital for GPA, highlighting COVID-19
Area of Science:
- Rheumatology
- Infectious Diseases
- Dermatology
Background:
- COVID-19 can manifest with cutaneous vasculitis.
- Granulomatosis with polyangiitis (GPA) is a vasculitis often involving pulmonary and diagnostic complications.
- Distinguishing GPA from COVID-19 symptoms can be challenging.
Observation:
- Presents the first documented case of new-onset GPA during active COVID-19 infection.
- Highlights the overlapping clinical symptoms between COVID-19 and GPA.
- Emphasizes the diagnostic complexities arising from concurrent conditions.
Findings:
- COVID-19 infection can trigger new-onset GPA.
- Rapid immunosuppressive therapy is crucial for managing GPA, even in the context of COVID-19.
- Skin manifestations of COVID-19 are diverse and can include vasculitis.
Implications:
- This case expands understanding of COVID-19's dermatological impact.
- Underscores the importance of considering GPA in COVID-19 patients presenting with vasculitic symptoms.
- Informs clinical decision-making for managing autoimmune conditions during viral infections.
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