Related Experiment Video

Updated: Nov 19, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.5K

New Onset Granulomatosis with Polyangiitis Associated with COVID-19

Moshe Y Bressler1,2, Naeha Pathak2, Kelly Cervellione3

  • 1New York Institute of Technology College of Osteopathic Medicine, Old Westbury, NY, USA.

Case Reports in Dermatological Medicine
|January 28, 2021
PubMed

Insights

This report details the first case of new-onset Granulomatosis with polyangiitis (GPA) in a patient with active COVID-19. Early immunosuppression is vital for GPA, highlighting COVID-19

Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Dermatology

Background:

  • COVID-19 can manifest with cutaneous vasculitis.
  • Granulomatosis with polyangiitis (GPA) is a vasculitis often involving pulmonary and diagnostic complications.
  • Distinguishing GPA from COVID-19 symptoms can be challenging.

Observation:

  • Presents the first documented case of new-onset GPA during active COVID-19 infection.
  • Highlights the overlapping clinical symptoms between COVID-19 and GPA.
  • Emphasizes the diagnostic complexities arising from concurrent conditions.

Findings:

  • COVID-19 infection can trigger new-onset GPA.
  • Rapid immunosuppressive therapy is crucial for managing GPA, even in the context of COVID-19.
  • Skin manifestations of COVID-19 are diverse and can include vasculitis.

Implications:

  • This case expands understanding of COVID-19's dermatological impact.
  • Underscores the importance of considering GPA in COVID-19 patients presenting with vasculitic symptoms.
  • Informs clinical decision-making for managing autoimmune conditions during viral infections.

More Related Videos

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-1906:29

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

Published on: May 25, 2022

2.6K
Granulocyte-dependent Autoantibody-induced Skin Blistering12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

10.7K

Related Concept Videos

COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.6K
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
415
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
1.8K
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
73
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
269
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
594