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Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

864
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Cancer Vaccines01:30

Cancer Vaccines

626
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
626

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Related Experiment Video

Updated: Nov 19, 2025

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
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Research progress in tumor targeted immunotherapy.

Yuelin Fang1, Aihua Yu1, Lei Ye1

  • 1Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan, PR China.

Expert Opinion on Drug Delivery
|January 28, 2021
PubMed
Summary

Tumor-targeted immunotherapy combines therapies for lasting cancer responses. This approach, utilizing novel nano delivery systems, offers hope for complete cancer cure and improved human health.

Keywords:
Cancer immunotherapyTreg cellsimmune checkpointsnanoparticlestargeted therapytumor-associated fibroblaststumor-associated macrophages

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Area of Science:

  • Oncology
  • Immunology
  • Nanotechnology

Background:

  • Traditional cancer treatments have limitations.
  • Tumor-targeted immunotherapy offers synergistic therapeutic effects.
  • This approach combines targeted therapy and immunotherapy for long-lasting responses.

Purpose of the Study:

  • To review the latest advancements in tumor-targeted immunotherapy.
  • To highlight novel strategies including TAMs, Treg cells, TAFs, and immune checkpoints.
  • To discuss the role of smart multifunctional nano delivery systems.

Main Methods:

  • Literature review of recent research in tumor-targeted immunotherapy.
  • Focus on emerging clinical trial data, particularly antibodies and inhibitors.
  • Analysis of immunotherapy's role in restoring anti-tumor immunity.

Main Results:

  • Tumor-targeted immunotherapy demonstrates potential for synergistic effects.
  • Smart multifunctional nano delivery systems are key to combining therapies.
  • Several targeted immunotherapies are progressing into clinical trials.

Conclusions:

  • Tumor-targeted immunotherapy is a promising strategy for cancer treatment.
  • It offers hope for complete cancer cure through enhanced immune surveillance.
  • Further research and clinical trials are crucial for its advancement.