Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Exosomes01:36

Overview of Exosomes

3.2K
Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
3.2K
Urine Studies I: Urinalysis01:29

Urine Studies I: Urinalysis

622
Urinalysis is a widely used diagnostic test that analyzes urine's physical, chemical, and microscopic characteristics. Healthcare providers use it to detect and monitor various health conditions, including renal disease, urinary tract infections (UTIs), diabetes, and metabolic or systemic disorders.Components of UrinalysisUrinalysis consists of three primary components: physical, chemical, and microscopic examination. Each provides unique insights into the urine sample and, by extension, the...
622

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effects of long-term aerobic exercise on prostate cancer-induced adipose tissue wasting: Browning to the rescue?

Cellular signalling·2026
Same author

Molecular regulation of PGC-1α: from protein-protein interactions and post-translational modifications to pharmacological modulation.

Journal of molecular medicine (Berlin, Germany)·2026
Same author

Strengthening animal welfare: monitoring humane endpoints in a rat model of mammary tumorigenesis undergoing a ladder resistance training protocol.

Laboratory animals·2026
Same author

Molecular predictors of incident frailty: a systematic review and critical appraisal of longitudinal evidence.

GeroScience·2026
Same author

Deciphering the circulating lipidome signature associated with physical performance in gastric cancer patients: an exploratory study.

Metabolomics : Official journal of the Metabolomic Society·2026
Same author

Enabling Next-Generation Mass Spectrometry-Based Proteomics: Standards, Proteoform Resolution, and FAIR, Reproducible, and Quantitative Analysis.

Proteomes·2026

Related Experiment Video

Updated: Nov 19, 2025

A Modified Precipitation Method to Isolate Urinary Exosomes
05:05

A Modified Precipitation Method to Isolate Urinary Exosomes

Published on: January 16, 2015

17.8K

What can urinary exosomes tell us?

Rui Vitorino1,2, Rita Ferreira3, Sofia Guedes3

  • 1Departamento de Cirurgia e Fisiologia, UnIC, Faculdade de Medicina da Universidade do Porto, Porto, Portugal. rvitorino@ua.pt.

Cellular and Molecular Life Sciences : CMLS
|January 28, 2021
PubMed
Summary

Urinary exosomes offer vital insights into disease pathophysiology and potential therapeutic targets. This review covers exosome isolation, novel biomarkers, and future trends in biomedical research.

Keywords:
BiomarkerDrug targetsExosomesUrine

More Related Videos

Isolation of Extracellular Vesicles from Murine Bronchoalveolar Lavage Fluid Using an Ultrafiltration Centrifugation Technique
09:18

Isolation of Extracellular Vesicles from Murine Bronchoalveolar Lavage Fluid Using an Ultrafiltration Centrifugation Technique

Published on: November 9, 2018

9.9K
Paper-based Devices for Isolation and Characterization of Extracellular Vesicles
11:53

Paper-based Devices for Isolation and Characterization of Extracellular Vesicles

Published on: April 3, 2015

11.7K

Related Experiment Videos

Last Updated: Nov 19, 2025

A Modified Precipitation Method to Isolate Urinary Exosomes
05:05

A Modified Precipitation Method to Isolate Urinary Exosomes

Published on: January 16, 2015

17.8K
Isolation of Extracellular Vesicles from Murine Bronchoalveolar Lavage Fluid Using an Ultrafiltration Centrifugation Technique
09:18

Isolation of Extracellular Vesicles from Murine Bronchoalveolar Lavage Fluid Using an Ultrafiltration Centrifugation Technique

Published on: November 9, 2018

9.9K
Paper-based Devices for Isolation and Characterization of Extracellular Vesicles
11:53

Paper-based Devices for Isolation and Characterization of Extracellular Vesicles

Published on: April 3, 2015

11.7K

Area of Science:

  • Biomedical research
  • Molecular biology
  • Pathophysiology

Background:

  • Exosomes are crucial for intercellular communication and homeostasis.
  • They act as molecular vehicles for drug delivery.
  • Exosomes are key in understanding disease mechanisms and drug discovery.

Purpose of the Study:

  • To review the significance of urinary exosomes in understanding disease pathophysiology.
  • To explore their potential as therapeutic targets.
  • To discuss exosome isolation methods and novel biomarkers.

Main Methods:

  • Review of current literature on urinary exosomes.
  • Analysis of exosome isolation techniques and technological advancements.
  • Highlighting novel urinary exosomal biomarkers and their clinical applicability.

Main Results:

  • Urinary exosomes provide valuable information for disease diagnosis and monitoring.
  • Novel biomarkers show potential for clinical application with emphasis on sensitivity and specificity.
  • Advancements in isolation methods improve exosome characterization.

Conclusions:

  • Urinary exosomes are significant for understanding human disease.
  • They hold promise as diagnostic biomarkers and therapeutic targets.
  • Future research trends focus on clinical validation and application.