Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Efficacy of a reduced-dosage PRRS MLV vaccine against a NADC34-like strain of porcine reproductive and respiratory syndrome virus.

Frontiers in veterinary science·2025

Same author

Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning.

Nature biotechnology·2025

Same author

The Selection and Validation of Reference Genes for RT-qPCR Analysis of the Predatory Natural Enemy <i>Orius nagaii</i> (Hemiptera: Anthocoridae).

Insects·2025

Same author

HMGA1 influence on iron-induced cell death in Tfh cells of SLE patients.

Cell biology and toxicology·2024

Same author

Microbial adaptation and genetic modifications for enhanced remediation in low-permeability soils.

The Science of the total environment·2024

Same author

A novel linear B cell epitope of the porcine circovirus type 3 capsid protein identified by phage display technology.

Journal of virological methods·2024

Same journal

Detection of cochlear microphonic for differential diagnosis between auditory neuropathy mice and noise-induced sensorineural hearing loss mice.

Journal of neuroscience methods·2026

Same journal

Assessment metrics for pain control in rats: A methodological commentary.

Journal of neuroscience methods·2026

Same journal

Infant EEG preprocessing pipelines: A capability framework and current gaps in practice.

Journal of neuroscience methods·2026

Same journal

Methods for Measuring Neural Activity During Voluntary Wheel Running.

Journal of neuroscience methods·2026

Same journal

Serotype-dependent differences in AAV cellular transduction rates in the hypothalamus of Arctic ground squirrels.

Journal of neuroscience methods·2026

Same journal

Rapid generation of human sensory neurons from iPSC for modeling of peripheral neuropathies.

Journal of neuroscience methods·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Nov 19, 2025

Visualizing the Developing Brain in Living Zebrafish using Brainbow and Time-lapse Confocal Imaging

Visualizing the Developing Brain in Living Zebrafish using Brainbow and Time-lapse Confocal Imaging

Published on: March 23, 2020

Tracking single cells in zebrafish brain.

Shan Zhao¹, Yu Qian¹, Yu Mu¹

¹Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai, 200031, China.

Journal of Neuroscience Methods

|January 28, 2021

Summary

This summary is machine-generated.

Tracking individual cell movements and shape changes in the larval zebrafish brain reveals how these dynamics influence brain function. This review highlights recent advances in understanding neuronal and non-neuronal cell behaviors.

Keywords:

Development Fluorescent imaging Morphology Single-cell tracking Whole-brain imaging Zebrafish

More Related Videos

Author Spotlight: Using Zebrafish to Explore Microglia Migration During Brain Development

Author Spotlight: Using Zebrafish to Explore Microglia Migration During Brain Development

Published on: May 17, 2024

Live Imaging of the Zebrafish Embryonic Brain by Confocal Microscopy

Live Imaging of the Zebrafish Embryonic Brain by Confocal Microscopy

Published on: April 1, 2009

Related Experiment Videos

Last Updated: Nov 19, 2025

Visualizing the Developing Brain in Living Zebrafish using Brainbow and Time-lapse Confocal Imaging

Visualizing the Developing Brain in Living Zebrafish using Brainbow and Time-lapse Confocal Imaging

Published on: March 23, 2020

Author Spotlight: Using Zebrafish to Explore Microglia Migration During Brain Development

Author Spotlight: Using Zebrafish to Explore Microglia Migration During Brain Development

Published on: May 17, 2024

Live Imaging of the Zebrafish Embryonic Brain by Confocal Microscopy

Live Imaging of the Zebrafish Embryonic Brain by Confocal Microscopy

Published on: April 1, 2009

Area of Science:

Neuroscience
Developmental Biology
Cell Biology

Background:

Brain development involves dynamic changes in cell location and morphology.
Observing these cellular dynamics is challenging due to dense cell packing.
Larval zebrafish offer a tractable model for in vivo cell tracking due to brain transparency.

Purpose of the Study:

To review recent advancements in single-cell tracking within the larval zebrafish brain.
To synthesize findings on neuronal and non-neuronal cell dynamics.
To connect cellular changes to overall brain function.

Main Methods:

Review of published literature on single-cell tracking studies.
Analysis of studies focusing on larval zebrafish models.
Categorization of observed cellular behaviors (migration, process dynamics, cell interactions).

Main Results:

Single-cell tracking in larval zebrafish has elucidated soma migration patterns.
Studies reveal dynamic process refinement in both neurons and non-neuronal cells.
Interactions between different cell types during development are increasingly understood.

Conclusions:

Cellular translocation and morphological alterations are fundamental to brain development and function.
Larval zebrafish provide critical insights into dynamic cellular processes shaping the brain.
Future research can build upon these findings to further unravel brain development mechanisms.