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Increase in arterial stiffness measures after bariatric surgery
Frances M Wang1, Chao Yang1, Hirofumi Tanaka2
1Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Atherosclerosis
|January 28, 2021
Summary
Bariatric surgery increased arterial stiffness measures, cardio-ankle vascular index (CAVI) and heart-ankle pulse wave velocity (haPWV), despite weight loss. Non-diabetic patients and those with greater heart rate reduction saw larger CAVI increases.
Area of Science:
- Cardiovascular Physiology
- Metabolic Surgery
- Vascular Biology
Background:
- Obesity's complex relationship with arterial stiffness is influenced by age and weight loss interventions.
- Limited understanding exists regarding arterial stiffness changes post-bariatric surgery.
- This study investigates arterial stiffness alterations and associated factors after bariatric procedures.
Purpose of the Study:
- To evaluate changes in arterial stiffness after bariatric surgery.
- To identify predictors of arterial stiffness changes post-surgery.
Main Methods:
- Assessed cardio-ankle vascular index (CAVI) and heart-ankle pulse wave velocity (haPWV) in 72 patients pre- and post-bariatric surgery (6 and 12 months).
- Evaluated changes in body mass index, heart rate, and blood pressure.
Main Results:
- Bariatric surgery led to decreased BMI, heart rate, and systolic blood pressure at 6 months.
- Arterial stiffness measures (CAVI and haPWV) significantly increased 6 and 12 months post-surgery.
- Greater CAVI increases were associated with being non-diabetic and larger post-surgery heart rate reductions.
Conclusions:
- Arterial stiffness (CAVI, haPWV) is elevated post-bariatric surgery, contrasting with other cardiometabolic improvements.
- Further research is needed to understand the mechanisms and implications of post-bariatric surgery arterial stiffness elevation.
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