Related Experiment Video
Updated: Nov 19, 2025
10:29
Experimental Methodology for Estimation of Local Heat Fluxes and Burning Rates in Steady Laminar Boundary Layer Diffusion Flames
Published on: June 1, 2016
12.1K
"FLAMES: A novel burning entity in MOG IgG associated disease"
Kshiteeja Jain1, Ajith Cherian1, Divya K P1
1Department of Neurology, Sree Chitra Tirunal institute for Medical Sciences and Technology, Kerala, India.
Multiple Sclerosis and Related Disorders
|January 28, 2021
Summary
FLAMES, a new subtype of MOG antibody disease, presents with seizures and characteristic cortical lesions on FLAIR MRI. This finding aids in differentiating FLAMES from other encephalitides.
Area of Science:
- Neurology
- Radiology
- Immunology
Background:
- Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) typically manifests as optic neuritis or myelitis.
- FLAMES (FLAIR imaging in MOG-associated Encephalitis with Seizures) represents a distinct clinico-radiological entity within MOGAD.
- FLAMES can mimic viral encephalitis due to its focal cortical presentation.
Discussion:
- FLAMES is characterized by hyperintense cortical lesions on FLAIR MRI, often accompanied by seizures.
- The presentation can be unilateral or bilateral cortical encephalitis.
- Advanced imaging techniques like MRA, SWI, and perfusion studies may aid in diagnosing FLAMES.
Key Insights:
- FLAMES expands the known spectrum of MOGAD presentations.
- Distinguishing FLAMES from other causes of encephalitis is crucial for appropriate management.
- Specific MRI findings are key to identifying this MOGAD subtype.
Outlook:
- Further research is needed to fully elucidate the pathophysiology of FLAMES.
- Establishing diagnostic criteria and treatment protocols for FLAMES will improve patient outcomes.
- Investigating the role of advanced imaging in MOGAD subtypes is warranted.
Related Concept Videos
01:16Flame Photometry: Lab
610
In a flame photometer, when a solution like potassium chloride is aspirated into the flame, the solvent evaporates, leaving behind dehydrated salt. This salt dissociates into free gaseous atoms in their ground state. Some of these atoms absorb energy from the flame, leading to their excitation. The excited atoms return to the ground state, emitting photons at characteristic wavelengths. Because only electronic transitions are involved, the resulting emission lines are very narrow. The intensity...
610
01:22Burn Injuries
3.4K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
3.4K
01:02Flame Photometry: Overview
1.1K
Flame photometry, also known as flame emission spectrometry, is a technique used for the qualitative and quantitative analysis of elements present in a sample using a flame as the source of excitation energy. The concept of flame photometry was realized in the early 1860s by Kirchhoff and Bunsen, who discovered that specific elements emit characteristic radiation when excited in flames. The first instrument developed for this purpose was used to measure sodium (Na) in plant ash using a Bunsen...
1.1K
01:30Inflammatory Bowel Disease II: Crohn's Disease
613
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
613
01:25Endocarditis II: Clinical Features of Infective Endocarditis
147
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
147
01:38Inflammation
57.8K
Overview
57.8K