Recent progress and challenges for polymeric microsphere compared to nanosphere drug release systems: Is there a real...

Area of Science:

• Materials Science
• Biomedical Engineering
• Drug Delivery Systems

Background:

• Polymeric microspheres (MSs) and nanospheres (NSs) are versatile drug carriers.
• They can encapsulate various therapeutics, including anticancer drugs.
• These systems offer advantages over conventional drug delivery methods.

Purpose of the Study:

• To describe and compare polymeric MSs and NSs as drug delivery systems.
• To highlight recent advances and challenges in the field.
• To provide insights for future progress in polymeric drug delivery.

Main Methods:

• Review of recent literature on polymeric microspheres and nanospheres for drug delivery.
• Comparative analysis of different polymeric carrier systems.
• Discussion of factors influencing drug release rates.

Main Results:

• Polymeric MSs and NSs enable controlled and sustained release of encapsulated drugs.
• These carriers offer advantages such as simple preparation, stimulus-responsive release, and applications in tissue engineering.
• Factors like porosity and scaffold stability influence drug release kinetics.

Conclusions:

• Polymeric microspheres and nanospheres represent a significant advancement in drug delivery technology.
• Further research is needed to overcome current challenges and fully realize their potential.
• The field requires focused efforts to progress towards more effective therapeutic applications.