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Databases for the study of biofilms: current status and potential applications
Fábio G Martins1,2, André Melo2, Sérgio F Sousa1
1UCIBIO/REQUIMTE, BioSIM - Departamento de Biomedicina, Faculdade de Medicina da Universidade do Porto, Porto, Portugal.
Biofouling
|January 29, 2021
Summary
Managing vast biofilm data is crucial for fighting infections and antibiotic resistance. This review examines new databases designed to organize this information, aiding future research and development.
Area of Science:
- Microbiology
- Bioinformatics
- Computational Biology
Background:
- Biofilms are implicated in over 80% of human infections and contribute to antibiotic resistance.
- The exponential growth of data in biofilm research necessitates advanced information management strategies.
Purpose of the Study:
- To review existing databases for managing biofilm data.
- To highlight the potential and challenges of these resources in the era of big data and machine learning.
Main Methods:
- Literature review of biofilm-related databases.
- Analysis of database applicability and potential for data organization and accessibility.
Main Results:
- Several databases (Quorumpeps, BiofOmics, BaAMPs, QSPpred, dPABBs, aBiofilm, Biofilms Structural Database) have been developed.
- These databases offer varying capabilities for handling biofilm research data.
Conclusions:
- Effective management of large-scale biofilm data is essential for scientific progress.
- Future challenges include optimizing database development and usage with big data and machine learning techniques.
