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Epidemiology of COVID-19 in Northern Ireland, 26 February 2020-26 April 2020
J Pett1,2, P McAleavey1, P McGurnaghan1
1Public Health Agency Northern Ireland, Belfast, Northern Ireland.
Insights
Household contacts experienced a significantly higher risk of SARS-CoV-2 infection, with a 15.9% secondary attack rate. This highlights the critical need for interventions to reduce transmission within households.
Area of Science:
- Epidemiology
- Infectious Disease Transmission
- Public Health
Background:
- Coronavirus disease 2019 (COVID-19) emerged globally in late 2019.
- Understanding transmission dynamics is crucial for effective control strategies.
- Enhanced surveillance and contact tracing are vital for monitoring outbreaks.
Purpose of the Study:
- To describe COVID-19 epidemiology in Northern Ireland (NI) from February to April 2020.
- To analyze contact tracing data to estimate secondary attack rates (SAR) for SARS-CoV-2.
- To determine the relative risk of infection among different contact categories.
Main Methods:
- Analysis of epidemiological data from Northern Ireland (February-April 2020).
- Examination of enhanced surveillance and contact tracing data (February-March 2020).
- Estimation of SAR and relative risk using logistic regression for SARS-CoV-2 contacts.
Main Results:
- COVID-19 incidence and mortality in NI were lower than in the rest of the UK.
- Household contacts had a SAR of 15.9%, over six times higher than 'high-risk' contacts (2.5%).
- Household contacts showed 11.0 times higher odds of testing positive for SARS-CoV-2 compared to other contacts.
Conclusions:
- The household is a primary setting for SARS-CoV-2 transmission.
- Interventions targeting household transmission are urgently needed.
- Further research is required to understand and mitigate household-based spread.
Abstract:
This paper describes the epidemiology of coronavirus disease 2019 (COVID-19) in Northern Ireland (NI) between 26 February 2020 and 26 April 2020, and analyses enhanced surveillance and contact tracing data collected between 26 February 2020 and 13 March 2020 to estimate secondary attack rates (SAR) and relative risk of infection among different categories of contacts of individuals with laboratory confirmed severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection. Our results show that during the study period COVID-19 cumulative incidence and mortality was lower in NI than the rest of the UK. Incidence and mortality were also lower than in the Republic of Ireland (ROI), although these observed differences are difficult to interpret given considerable differences in testing and surveillance between the two nations. SAR among household contacts was 15.9% (95% CI 6.6%-30.1%), over 6 times higher than the SAR among 'high-risk' contacts at 2.5% (95% CI 0.9%-5.4%). The results from logistic regression analysis of testing data on contacts of laboratory-confirmed cases show that household contacts had 11.0 times higher odds (aOR: 11.0, 95% CI 1.7-70.03, P-value: 0.011) of testing positive for SARS-CoV-2 compared to other categories of contacts. These results demonstrate the importance of the household as a locus of SARS-CoV-2 transmission, and the urgency of identifying effective interventions to reduce household transmission.
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