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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Related Experiment Video

Updated: Nov 19, 2025

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
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Primary thyroid squamous cell carcinoma: a challenging management problem.

Joshua Agilinko1, Tze Jun Kueh2, Louise Smart2

  • 1Department of Otolaryngology-Head and Neck Surgery, Aberdeen Royal Infirmary, Aberdeen, UK.

BMJ Case Reports
|January 29, 2021
PubMed
Summary
This summary is machine-generated.

Primary thyroid squamous cell carcinoma (SCC) is a rare, aggressive cancer. This case study shows successful treatment with surgery and radiotherapy, significantly extending survival beyond the typical 7 months.

Keywords:
cancer interventionotolaryngology / ENTthyroid disease

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Area of Science:

  • Oncology
  • Head and Neck Surgery

Background:

  • Primary thyroid squamous cell carcinoma (SCC) is a rare and aggressive malignancy.
  • Standard diagnostic procedures include ultrasonography, biopsy, and CT scans.
  • Treatment options comprise surgery, radiotherapy, and chemotherapy.

Observation:

  • A patient with advanced primary thyroid SCC presented for treatment.
  • The patient underwent surgical intervention and radiotherapy.

Findings:

  • The patient achieved successful treatment outcomes.
  • Survival extended to 2 years, significantly exceeding the reported 7-month mean survival rate for this condition.

Implications:

  • This case highlights the potential efficacy of combined surgery and radiotherapy for advanced thyroid SCC.
  • Aggressive treatment strategies may improve survival in rare, high-grade thyroid cancers.
  • Further research into optimal treatment protocols for primary thyroid SCC is warranted.