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Retinoblastoma: What the Neuroradiologist Needs to Know
V M Silvera1, J B Guerin1, W Brinjikji1,2
1From the Departments of Neuroradiology (V.M.S., J.B.G., W.B.).
AJNR. American Journal of Neuroradiology
|January 29, 2021
Summary
Retinoblastoma, a common childhood eye tumor, requires early diagnosis for optimal survival and vision. This review highlights neuroradiology
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Neuroradiology
Background:
- Retinoblastoma is the most frequent primary intraocular tumor in children.
- Early diagnosis is crucial for maximizing patient survival, globe salvage, and visual acuity.
- Individualized management based on clinical and imaging features necessitates a multidisciplinary team approach.
Purpose of the Study:
- To review the clinical presentation of retinoblastoma.
- To discuss ophthalmic and neuroradiology imaging modalities for diagnosis and prognosis.
- To outline current treatment options, including the role of interventional neuroradiology.
Main Methods:
- Review of clinical presentation of retinoblastoma.
- Discussion of ophthalmic imaging modalities.
- Analysis of neuroradiology imaging features and their diagnostic/prognostic significance.
- Overview of current treatment strategies, including intra-arterial chemotherapy.
Main Results:
- Characteristic diagnostic and prognostic imaging features are essential for neuroradiologists.
- Intra-arterial chemotherapy is increasingly adopted for globe salvage.
- Interventional neuroradiologists play a significant role in retinoblastoma treatment.
Conclusions:
- Accurate diagnosis and individualized management are key to optimizing outcomes in retinoblastoma.
- Neuroradiology is integral to the multidisciplinary care of retinoblastoma patients.
- The evolving role of interventional neuroradiology in treatment is highlighted.
