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Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection

Published on: March 14, 2019

Brevibacteria tibial osteomyelitis.

Yehuda Eidensohn¹, Abraham Wei², Michael Sirkin³

¹Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ, United States.

|January 29, 2021

Summary

This summary is machine-generated.

Brevibacteria, typically found on skin, can rarely cause serious bone infections like osteomyelitis, especially in individuals with medical implants. This case highlights challenges in identifying this unusual pathogen.

Keywords:

Brevibacterium Implanted hardware Osteomyelitis Tibial infection

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Area of Science:

Microbiology
Infectious Diseases
Orthopedics

Background:

Brevibacteria are Gram-positive bacteria commonly inhabiting human skin and dairy products.
While generally commensal, rare instances link Brevibacterium species to severe human infections.

Observation:

A case of tibial osteomyelitis caused by Brevibacterium species is presented.
The patient was immunocompetent and had implanted hardware, a potential factor in infection development.

Findings:

Brevibacteria, though uncommon pathogens, can lead to challenging osteomyelitis cases.
Accurate identification of Brevibacterium species is crucial for appropriate treatment.

Implications:

This case underscores the need to consider Brevibacterium in the differential diagnosis of osteomyelitis, particularly with foreign bodies.
Enhanced diagnostic approaches may be required for recognizing these rare bacterial infections.