Related Experiment Video
Updated: Nov 19, 2025
08:52
Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant
Published on: May 27, 2011
17.5K
Stem Cell Therapy Potency in Personalizing Severe COVID-19 Treatment
Arefeh Basiri1,2, Fatemeh Mansouri2,3,4, Arezo Azari2,5
1Department of Biomaterials and Tissue Engineering, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Stem Cell Reviews and Reports
|January 29, 2021
Summary
Personalized medicine, particularly stem cell therapies like mesenchymal stem cells (MSCs), shows theoretical promise for treating severe COVID-19. Research reviews their immune-modulatory effects and potential for future personalized treatments.
Area of Science:
- Immunology
- Genomics
- Regenerative Medicine
Background:
- Severe COVID-19 lacks specific treatments, with symptoms varying due to genomic differences.
- Personalized medicine and cell-based therapies offer potential solutions for complex conditions.
Purpose of the Study:
- To review current literature on personalized medicine and cell-based therapies for severe COVID-19.
- To explore the theoretical application of personalized medicine, focusing on stem cells, for COVID-19 treatment.
Main Methods:
- Literature review of published papers and concepts on personalized medicine and cell-based therapy.
- Focus on stem cell therapies, particularly mesenchymal stem cells (MSCs), for their immune-modulatory properties.
Main Results:
- Mesenchymal stem cells (MSCs) possess immune-modulatory effects and can be stored for personalized applications.
- Evidence suggests MSCs are safe and potent for immune-mediated inflammatory and incurable diseases.
Conclusions:
- Personalized medicine, especially stem cell therapy, holds theoretical potential for severe COVID-19.
- Further clinical studies are warranted to validate the efficacy and safety of MSC-based therapies in COVID-19.
Related Concept Videos
01:21Stem Cell Therapy for Tissue Regeneration
4.4K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.4K
01:17Stem Cell Culture
5.8K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
5.8K
01:22iPS Cell Differentiation
2.9K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
2.9K
01:06Induced Pluripotent Stem Cells
4.9K
Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
Somatic...
4.9K
01:13Induced Pluripotent Stem Cells
25.4K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
25.4K
01:27Source And Potency Of Stem Cells
5.7K
Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
5.7K