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Potential COVID-19 Therapeutic Agents and Vaccines: An Evidence-Based Review
Elnaz Khani1, Sajad Khiali1, Taher Entezari-Maleki1,2
1Department of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract:
Since the early days of 2020, the severe acute respiratory syndrome coronavirus 2 pandemic has become a global health concern. Currently, some therapies and vaccines have received US Food and Drug Administration approval or emergency use authorization for the management of coronavirus disease 2019. According to the pathophysiology of the disease, several medications have been evaluated in different clinical conditions of the disease. Evidence-based reviewing and categorizing these medications can guide the clinicians to select the proper medications according to each patient's condition. Therefore, we performed this review to categorize the coronavirus disease 2019 potential therapeutics and vaccines.
Insights
This review categorizes potential therapeutics and vaccines for coronavirus disease 2019 (COVID-19). Evidence-based review guides clinicians in selecting appropriate COVID-19 treatments based on patient condition.
Area of Science:
- Infectious Diseases
- Virology
- Pharmacology
Background:
- The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, beginning in early 2020, poses a significant global health challenge.
- Approved therapies and vaccines are available for managing coronavirus disease 2019 (COVID-19), with ongoing evaluation of various medications based on disease pathophysiology.
Purpose of the Study:
- To systematically review and categorize potential therapeutics for COVID-19.
- To provide an evidence-based resource for clinicians to select appropriate treatments for COVID-19 patients.
Main Methods:
- Conducted an evidence-based review of existing literature.
- Categorized potential COVID-19 therapeutics and vaccines based on scientific evidence and clinical application.
Main Results:
- Identified and categorized various therapeutic agents and vaccines evaluated for COVID-19 management.
- Summarized the evidence supporting the efficacy and application of different treatment options.
Conclusions:
- A categorized overview of COVID-19 therapeutics and vaccines can aid clinical decision-making.
- Evidence-based categorization supports personalized treatment strategies for patients with COVID-19.
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