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Coronavirus Disease 2019 Infection in Children With Sickle Cell Disease: Case Series From Oman

Amal Al Sabahi1, Nawal Al Maskari2, Ibrahim Al Busaidi3

  • 1Department of Paediatric Hematology and Oncology, The National Oncology Centre.

Journal of Pediatric Hematology/Oncology
|January 29, 2021
PubMed

Insights

This study reports on five Omani children with sickle cell disease (SCD) who contracted COVID-19. All pediatric patients with sickle cell disease recovered, highlighting the need for further research on COVID-19 outcomes in this population.

Area of Science:

  • Pediatric Hematology
  • Infectious Diseases
  • Global Health

Background:

  • The COVID-19 pandemic poses significant risks to vulnerable populations, including individuals with sickle cell disease (SCD).
  • Limited data exist on the impact of COVID-19 on pediatric patients with SCD.
  • This study addresses the gap in understanding COVID-19's effects on children with SCD.

Observation:

  • A case series of five Omani children diagnosed with sickle cell disease and subsequently infected with COVID-19 is presented.
  • The report details the varied clinical presentations, management strategies, and outcomes for these pediatric patients.
  • This series provides insights into the specific challenges and responses related to COVID-19 in children with SCD.

Findings:

  • All five pediatric patients with sickle cell disease who contracted COVID-19 successfully recovered.
  • The case series illustrates diverse clinical manifestations and successful management approaches in this cohort.
  • Despite being a high-risk group, the observed pediatric SCD patients showed positive recovery from COVID-19.

Implications:

  • The findings suggest that pediatric patients with sickle cell disease may recover from COVID-19, contrary to initial high-risk assumptions.
  • Further large-scale studies are crucial to validate these observations and establish definitive conclusions regarding COVID-19 outcomes in pediatric SCD.
  • This research contributes to the understanding of COVID-19's impact on pediatric hematological conditions and informs clinical management guidelines.
Abstract

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