Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Conventional computerized tomography of the heart.

K Lackner1, P Landwehr, P Thurn

  • 1Institut für Röntgendiagnostik, Universität Würzburg, BRD.

International Journal of Cardiac Imaging
|January 1, 1988
PubMed
Summary

Cardiovascular computed tomography (CT) offers valuable morphological insights into various heart conditions. While ECG-gated cardio-CT provides quantitative functional data, its time resolution limits accuracy for ejection fraction calculations.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gendered analysis of care work burden and mental health using data from the Gutenberg Covid-19 study.

Scientific reports·2025
Same author

Aramchol in patients with nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled phase 2b trial.

Nature medicine·2021
Same author

Large-scale identification of functional microRNA targeting reveals cooperative regulation of the hemostatic system.

Journal of thrombosis and haemostasis : JTH·2018
Same author

Prevalence of depression and anxiety among participants with glaucoma in a population-based cohort study: The Gutenberg Health Study.

BMC ophthalmology·2018
Same author

Homocysteine concentration in coronary artery disease: Influence of three common single nucleotide polymorphisms.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2016
Same author

Association of Type D personality with cognitive functioning in individuals with and without cardiovascular disease - The Gutenberg Health Study.

International journal of cardiology·2016

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Cardiac CT

Background:

  • Ungated cardiac computed tomography (CT) is useful for assessing cardiac morphology in conditions like congenital heart disease, cardiac masses, and calcifications.
  • It allows qualitative evaluation of myocardial thickness and coronary bypass graft perfusion.

Purpose of the Study:

  • To evaluate the capabilities of ECG-gated cardiac CT for quantitative assessment of cardiac function and morphology.
  • To compare the diagnostic performance of cardiac CT with other imaging modalities.

Main Methods:

  • Utilized ECG-gated cardiac CT for quantitative analysis of myocardial thickness, cardiac cavity volumes, and functional parameters.
  • Compared left ventricular ejection fraction derived from ECG-gated cardiac CT with laevocardiography.
  • Assessed regional wall motion analysis using cardiac CT.

Main Results:

  • ECG-gated cardiac CT enables quantitative assessment of systolic and diastolic function and cardiac volumes.
  • Correlation between left ventricular ejection fraction from ECG-gated cardiac CT and laevocardiography was poor (r=0.7) due to limited temporal resolution of CT.
  • Quantitative analysis of regional wall motion demonstrated 80.5% specificity, 73.9% sensitivity, and 75.7% accuracy for diagnosing pathological wall motion.

Conclusions:

  • Cardiac CT, particularly ECG-gated protocols, provides comprehensive morphological and functional information about the heart.
  • Limitations in temporal resolution affect quantitative functional assessments like ejection fraction.
  • Potential side effects include fluid retention and cardiac volume loading from contrast media, necessitating careful patient selection.

Related Experiment Videos