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Author Spotlight: A Comprehensive Protocol for Acinetobacter Biofilm Quantification, Assessment, and Visualization
Published on: August 4, 2023
Acinetobacter baumannii: Its Clinical Significance in Human and Veterinary Medicine
Francesca Paola Nocera1, Anna-Rita Attili2, Luisa De Martino1
1Department of Veterinary Medicine and Animal Production, University of Naples "Federico II", 80137 Naples, Italy.
Abstract:
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen, causing severe infections difficult to treat. The A. baumannii infection rate has increased year by year in human medicine and it is also considered as a major cause of nosocomial infections worldwide. This bacterium, also well known for its ability to form biofilms, has a strong environmental adaptability and the characteristics of multi-drug resistance. Indeed, strains showing fully resistant profiles represent a worrisome problem in clinical therapeutic treatment. Furthermore, A. baumannii-associated veterinary nosocomial infections has been reported in recent literature. Particularly, carbapenem-resistant A. baumannii can be considered an emerging opportunistic pathogen in human medicine as well as in veterinary medicine.
Insights
Acinetobacter baumannii, a multidrug-resistant pathogen, causes severe hospital infections in humans and animals. Carbapenem-resistant strains are an increasing global concern for both human and veterinary medicine.
Area of Science:
- Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Background:
- Acinetobacter baumannii is a Gram-negative opportunistic pathogen.
- It is a significant cause of nosocomial infections worldwide.
- The bacterium exhibits strong environmental adaptability and multi-drug resistance.
Purpose of the Study:
- To highlight the increasing prevalence of Acinetobacter baumannii infections.
- To emphasize the challenges posed by multi-drug resistant strains.
- To address the emerging threat of carbapenem-resistant Acinetobacter baumannii in both human and veterinary medicine.
Main Methods:
- Literature review of Acinetobacter baumannii infections.
- Analysis of infection rates and resistance profiles.
- Examination of clinical and veterinary case reports.
Main Results:
- Acinetobacter baumannii infections are increasing in human medicine.
- Multi-drug resistant strains, particularly carbapenem-resistant ones, are a significant clinical problem.
- Veterinary nosocomial infections associated with Acinetobacter baumannii have been reported.
Conclusions:
- Acinetobacter baumannii poses a growing threat due to its resistance.
- Carbapenem-resistant strains represent an emerging opportunistic pathogen in both human and veterinary fields.
- Effective therapeutic strategies are urgently needed to combat these infections.
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