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Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
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Nutrigenomics: lessons learned and future perspectives.

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Omics technologies like metabolomics are crucial for precision nutrition, revealing individual responses to diet. These advanced tools offer insights into dietary biomarkers and personalized health strategies.

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Area of Science:

  • Nutrition Science
  • Biotechnology
  • Human Health

Background:

  • Omics technologies (metabolomics, transcriptomics, proteomics, metagenomics) are vital in modern nutrition science.
  • Understanding individual responses to diet is key for precision nutrition.
  • These technologies advance mechanistic insights into dietary interventions.

Purpose of the Study:

  • To review the impact of omics technologies in human nutrition studies.
  • To highlight the role of omics in precision nutrition development.
  • To assess the current evidence supporting omics in nutritional research.

Main Methods:

  • Review of existing human nutrition studies incorporating omics data.
  • Analysis of metabolomics, proteomics, transcriptomics, and metagenomics applications.
  • Examination of biomarker development for dietary assessment.

Main Results:

  • Omics data show low intra-individual and high inter-individual variability.
  • Metabolomics aids in developing biomarkers for food intake and dietary assessment.
  • Evidence supports the use of omics technologies in nutrition science, often from pilot studies.

Conclusions:

  • Omics technologies are essential for advancing precision nutrition.
  • Further research is needed to integrate omics biomarkers with current dietary assessment strategies.
  • Integrating omics from study inception and fostering collaborations are crucial for future success.