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Does methotrexate cause progressive fibrotic interstitial lung disease? A systematic review

Julie K Dawson1, Edmond Quah2, Ben Earnshaw2

  • 1Department of Rheumatology St Helens Hospital, St Helens and Knowsley Trust Hospitals, Marshalls Cross Road, St Helens, Merseyside, UK. julie.dawson@sthk.nhs.uk.

Rheumatology International
|January 30, 2021
PubMed
Summary

Methotrexate (MTX) does not cause fibrotic interstitial lung disease (fILD). Higher quality studies indicate MTX is not linked to fILD and may even improve outcomes in rheumatoid arthritis patients with fILD.

Keywords:
Fibrotic interstitial lung diseaseMethotrexateMethotrexate-induced pneumonitisProgressive

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