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Updated: Nov 19, 2025

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
Published on: March 19, 2016
Visual analysis of flow and diffusion of hemolytic agents and hematomas
Yafei Zhu1, Mengyao Bao1, Miaomiao Jiang2
1College of Sciences, North China University of Science and Technology, Tangshan, 063210, Hebei, China.
Abstract:
The elimination of intracranial hematomas has received widespread attention and the interactions between hemolytic agents and hematomas have become a hot research topic. In this study, we used the Navier-Stokes equation to describe the flow control equation for hemolytic agents in a tube and used Fick's law and the Maxwell-Stefan diffusion theory to describe the diffusion and mass transfer of hemolytic agents and hematomas. The physical fields and initial boundary conditions were set according to the parametric properties of the fluid and drainage tube. The COMSOL Multiphysics software was used to simulate the streamline distribution of hemolytic agents in a bifurcated drainage tube. Additionally, the diffusion behaviors of the hemolytic agents into hematomas were simulated and visual analysis of coupled multiphysics was performed to realize the digitization and visualization of engineering fluid problems and contribute to the field of medical engineering.
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