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Published on: September 25, 2019
Interpretation of fluid-attenuated inversion recovery vascular hyperintensity in stroke
Kyung-Yul Lee1, Jin Woo Kim2, Mina Park2
1Department of Neurology, Gangnam Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea.
Abstract:
Fluid-attenuation inversion recovery (FLAIR) vascular hyperintensity (FVH) is a common presentation on brain magnetic resonance images of patients with acute ischemic stroke. This sign is known as a sluggish collateral flow. Although FVH represents the large ischemic penumbra and collateral circulation, the clinical significance of FVH has not been established. Varying protocols for FLAIR, treatment differences, and heterogeneity of endpoints across studies have complicated the interpretation of FVH in patients with acute stroke. In this review article, we describe the mechanism of FVH, as well as its association with functional outcome, perfusion-weighted images, and large artery stenosis. In addition, we review the technological variables that affect FVH and discuss the future perspectives.
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