Related Experiment Video
Updated: Nov 19, 2025

Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
Published on: October 14, 2022
Using a Data-Driven Improvement Methodology to Decrease Surgical Site Infections in a Community Neurosurgery
Panagiotis Kerezoudis1, Parker C Kelley2, Charles R Watts3
1Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
A new protocol significantly reduced surgical site infections in neurosurgery patients, decreasing the rate from 6.7% to 0.96%. This quality improvement initiative enhanced patient safety and care value.
Area of Science:
- Neurosurgery
- Infectious Disease Control
- Quality Improvement
Background:
- Surgical site infections (SSIs) pose a significant risk to neurosurgical patients.
- Existing protocols for preoperative antibiotic use and infection prevention had limitations.
Purpose of the Study:
- To implement and evaluate a data-driven methodology to decrease the departmental surgical site infection rate in neurosurgery.
- To achieve a target SSI rate of 1%.
Main Methods:
- A prospective interventional study with historical controls was conducted.
- Interventions included optimized preoperative chlorhexidine showers, methicillin-sensitive Staphylococcus aureus (MSSA)/methicillin-resistant Staphylococcus aureus (MRSA) screening and decolonization, and an optimized preoperative antibiotic order set.
- The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) was used for surveillance.
Main Results:
- Analysis of 317 NSQIP neurosurgical cases (163 pre-implementation, 154 post-implementation) showed no significant demographic differences, except for inpatient and functional status.
- The SSI rate decreased from 6.7% to 0.96% post-implementation.
- The implementation cost was $27,179, averaging $58 per patient.
Conclusions:
- Systematic investigation of clinical practice gaps is crucial for enhancing patient safety in neurosurgery.
- Quality improvement projects can effectively increase patient safety and the value of care.
- The implemented protocol demonstrated significant success in reducing SSIs.
Related Concept Videos
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Asepsis
Peripheral Artery Disease V: Postoperative Nursing Management
Aneurysm IV: Nursing Management
Cardiomyopathy VII: Pre and Post Operative Nursing Management

