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Comparison of machine learning models to classify Auditory Brainstem Responses recorded from children with Auditory

Hasitha Wimalarathna1, Sangamanatha Ankmnal-Veeranna2, Chris Allan3

  • 1Department of Electrical & Computer Engineering, Western University, London, Ontario, Canada; National Centre for Audiology, Western University, London, Ontario, Canada.

Computer Methods and Programs in Biomedicine
|January 30, 2021
PubMed
Summary

Machine learning models can automate auditory brainstem response (ABR) analysis for children with listening difficulties. The Xgboost algorithm achieved 92% accuracy, offering a potential clinical tool for audiologists.

Keywords:
Auditory Brainstem ResponsesAuditory Processing DisorderMachine LearningSignal feature extraction

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Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Machine Learning

Background:

  • Auditory brainstem responses (ABRs) assess auditory nervous system integrity in individuals with listening difficulties.
  • Manual ABR interpretation by audiologists requires expertise and can be prone to error.
  • Machine learning (ML) offers a promising approach to automate ABR analysis and enhance diagnostic accuracy.

Purpose of the Study:

  • To identify a suitable ML technique for automating ABR analysis within the Auditory Processing Disorder (APD) clinical test battery.
  • To reduce human error and improve the efficiency of ABR interpretation in clinical settings.

Main Methods:

  • Analyzed ABR responses from 136 children evaluated for auditory processing difficulties.
  • Applied various ML algorithms including SVM, RF, DT, GB, Xgboost, and NN.
  • Utilized signal feature extraction techniques and statistical testing to determine the most robust model.

Main Results:

  • Identified clinically significant time-frequency signal features.
  • The Xgboost ML model demonstrated the highest robustness and accuracy at 92%.
  • This model effectively identified neurological abnormalities in ABR waveforms.

Conclusions:

  • Accurate ML models can automate suprathreshold ABR waveform analysis.
  • This research is expected to lead to an ML-based screening tool for audiologists.
  • The findings may guide future development of ML paradigms to enhance clinical audiology test batteries.