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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Hypertension, Prehypertension, Hypertensive Heart Disease, and Atrial Fibrillation

Dennis H Lau1, Hassan A Shenasa2, Mohammad Shenasa2

  • 1Department of Cardiology, Centre for Heart Rhythm Disorders, University of Adelaide, Royal Adelaide Hospital, Port Road, Adelaide, South Australia 5000, Australia.

Cardiac Electrophysiology Clinics
|January 31, 2021
PubMed

Insights

Hypertension is a major risk factor for atrial fibrillation (AF). Managing blood pressure and other risk factors is crucial for effective AF treatment and prevention, requiring a multidisciplinary approach.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Electrophysiology

Background:

  • Hypertension (HT) is the leading risk factor for developing atrial fibrillation (AF).
  • Emerging data link pre-hypertension and aortic stiffness to higher AF incidence and recurrence.
  • Atrial remodeling caused by HT is progressive yet potentially reversible.

Purpose of the Study:

  • To review the relationship between hypertension and atrial fibrillation.
  • To discuss the role of blood pressure management in AF.
  • To emphasize integrated care strategies for patients with HT and AF.

Main Methods:

  • Literature review and synthesis of current research on hypertension and atrial fibrillation.
  • Analysis of data regarding pre-HT, aortic stiffness, and AF.
  • Discussion of treatment strategies, including renin-angiotensin-aldosterone system inhibition.

Main Results:

  • Hypertension significantly increases the risk of AF.
  • Aortic stiffness and pre-HT are associated with increased AF risk.
  • Optimal blood pressure targets for individuals with both HT and AF are not yet definitively established.

Conclusions:

  • Integrated care and comprehensive risk factor management are essential for AF treatment.
  • Targeting multiple AF risk factors, alongside hypertension, is key.
  • Multidisciplinary team involvement improves outcomes for patients with HT and AF.

Keywords:
Atrial fibrillationHypertensionPrehypertensionRemodelingRenin-angiotensin aldosterone systemRisk factor management

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