De novo proteins from random sequences through in vitro evolution

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Updated: Nov 19, 2025

In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity
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Cher Ling Tong1, Kun-Hwa Lee1, Burckhard Seelig1

  • 1Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, USA; BioTechnology Institute, University of Minnesota, St. Paul, MN, USA.

Current Opinion in Structural Biology
|January 31, 2021
PubMed

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