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Updated: Nov 19, 2025

Tibial Nerve Transection - A Standardized Model for Denervation-induced Skeletal Muscle Atrophy in Mice
Published on: November 3, 2013
COVID-19 related muscle denervation atrophy
S Bahouth1, K Chuang2, L Olson3
1Division of Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, YAW 6048, Boston, MA, 02114, USA. sbahouth@mgh.harvard.edu.
This study details unusual MRI findings in a rare peripheral neuropathy case linked to COVID-19. The presentation mimics Guillain-Barre syndrome but shows distinct clinical and radiological differences.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- COVID-19 is known to cause neurological symptoms, with Guillain-Barre syndrome and critical illness polyneuropathy being common peripheral neuropathies.
- Peripheral neuropathies represent a diverse group of neurological disorders affecting the peripheral nervous system.
Observation:
- This paper describes a unique case of peripheral neuropathy in a patient with COVID-19.
- The patient exhibited distinct magnetic resonance imaging (MRI) findings that were not typical for standard COVID-19-associated neuropathies.
Findings:
- The observed MRI findings share similarities with Guillain-Barre syndrome and its variants.
- However, key clinical and radiological features differentiate this case from the classic presentation of Guillain-Barre syndrome.
Implications:
- These findings expand the understanding of COVID-19's neurological manifestations.
- Recognizing these distinct MRI patterns is crucial for accurate diagnosis and management of unusual neuropathies in COVID-19 patients.
- Further research is warranted to elucidate the pathophysiology of these distinct presentations.
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