High sugar content and body mass index: modelling pathways around the first 1000 d of life, BRISA cohort

Dâmaris Alves Silva Pinto1, Joelma Ximenes Prado Teixeira Nascimento2, Luana Lopes Padilha1

  • 1Programa de Pós-Graduação em Saúde Coletiva, Universidade Federal do Maranhão, 155 Barão de Itapary-Centro, São Luís, MA 65020-070, Brasil.

Public Health Nutrition
|February 1, 2021
PubMed

Insights

Maternal obesity and high sugary drink intake during pregnancy increase children's early exposure to added sugars. These unhealthy dietary patterns often persist through the first 1000 days of life, impacting long-term health.

Area of Science:

  • Public Health
  • Nutritional Epidemiology
  • Child Development

Background:

  • Limited research exists on sugar consumption during the critical first 1000 days of life.
  • Understanding early life dietary habits is crucial for preventing long-term health issues.

Purpose of the Study:

  • To model the relationship between maternal pre-pregnancy BMI and sugary drink consumption during pregnancy.
  • To investigate the impact on children's early exposure to high-sugar products and BMI z-score by age two.

Main Methods:

  • Utilized data from the BRISA cohort in São Luís, Brazil.
  • Employed structural equation modeling to analyze prenatal factors, birth weight, breastfeeding, and early childhood dietary intake and BMI.

Main Results:

  • Higher maternal pre-pregnancy BMI and increased sugary drink consumption during pregnancy were linked to higher intake of added sugars in children by age two.
  • No significant effect on offspring weight was observed at this early stage.

Conclusions:

  • Maternal obesity and high sugary drink consumption during pregnancy contribute to increased early childhood exposure to added sugars.
  • These findings highlight the perpetuation of unhealthy dietary behaviors within the first 1000 days of life.
Abstract

Related Concept Videos

Glucose Absorption Into the Small Intestine01:26

Glucose Absorption Into the Small Intestine

Complex carbohydrates consumed cannot be absorbed into the small intestine in their original form. First, they must be hydrolyzed to a monosaccharide form such as glucose or galactose. These monosaccharides are then transported across the intestinal membrane and into the blood via transcellular transport. The intestinal epithelial cells allow the movement of these monosaccharides with a defined 'entry' through membrane transporter proteins present on their apical membrane and...
33.8K
Glucose Homeostasis: Regulation of Blood Glucose01:02

Glucose Homeostasis: Regulation of Blood Glucose

Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
3.2K
Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
1.7K
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
925
Sugars as Energy Storage Molecules01:10

Sugars as Energy Storage Molecules

Sugar (a simple carbohydrate) metabolism (chemical reactions) is a classic example of the many cellular processes that use and produce energy. Living things consume sugar as a major energy source because sugar molecules have considerable energy stored within their bonds. Consumed carbohydrates have their origins in photosynthesizing organisms like plants. During photosynthesis, plants use the energy of sunlight to convert carbon dioxide gas into sugar molecules, like glucose. Because this...
9.3K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
3.8K