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Bone marrow transplantation for acute leukemia using a histocompatible paternal donor
Acta Haematologica
|January 1, 1979
Summary
A bone marrow transplant was performed for acute lymphoblastic leukemia. The patient experienced engraftment but died from cytomegalovirus-induced pneumonitis, with leukemia recurrence noted.
Area of Science:
- Hematology
- Immunology
- Oncology
Background:
- Acute lymphoblastic leukemia (ALL) poses treatment challenges, especially when resistant to conventional therapies.
- Bone marrow transplantation (BMT) is a potential curative option for refractory leukemia.
- Human leukocyte antigen (HLA)-identical sibling or unrelated donor transplants are standard, but alternative donors like HLA-identical parents are explored.