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Histoplasmosis and inflammatory bowel disease: A case report
Dushyant Dahiya1, Asim Kichloo1, Jagmeet Singh2
1Internal Medicine, Central Michigan University, Saginaw, MI 48603, United States.
Gastrointestinal histoplasmosis can mimic inflammatory bowel disease (IBD), presenting with abdominal pain and diarrhea. Early diagnosis and treatment with itraconazole are crucial for symptom resolution.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Mycology
Background:
- Disseminated Histoplasma capsulatum infection can affect the gastrointestinal tract.
- Symptoms may include abdominal pain and inflammatory diarrhea, closely resembling inflammatory bowel disease (IBD).
Observation:
- A 41-year-old male presented with fever, severe abdominal pain, diarrhea, and hematochezia.
- Initial assessment suggested an IBD exacerbation, but urine Histoplasma antigen testing was positive.
Findings:
- The patient improved significantly after treatment with itraconazole.
- This confirmed a diagnosis of gastrointestinal histoplasmosis.
Implications:
- Highlights the importance of considering fungal infections in IBD differentials.
- Emphasizes prompt diagnosis and management of gastrointestinal histoplasmosis.
- Reviews IBD, chronic diarrhea evaluation, and gastrointestinal histoplasmosis.
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