Related Experiment Video
Updated: Nov 19, 2025

Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
Published on: October 18, 2024
Recurrent Pneumothorax with CPAP Therapy for Obstructive Sleep Apnea
Kartikeya Rajdev1, Pretty Sara Idiculla2, Shubham Sharma3
1Department of Internal Medicine, Division of Pulmonary, Critical Care & Sleep Medicine, University of Nebraska Medical Center, 42nd and Emile St., Omaha, Nebraska 68198-7400, USA.
Continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) can rarely cause pneumothorax (PTX). This case report highlights the risk of pulmonary barotrauma associated with CPAP use in OSA patients.
Area of Science:
- Pulmonology
- Sleep Medicine
- Critical Care Medicine
Background:
- Pulmonary barotrauma, like pneumothorax (PTX), is a recognized complication of invasive mechanical ventilation.
- It is infrequently documented with noninvasive positive pressure ventilation (NPPV) and continuous positive airway pressure (CPAP) therapy.
Observation:
- A 66-year-old female with chronic dyspnea and obstructive sleep apnea (OSA) developed recurrent pneumothorax (PTX) after initiating CPAP therapy.
- The patient experienced three separate PTX events over several months, temporally linked to her CPAP use.
Findings:
- This case report underscores the potential risk of barotrauma, specifically PTX, associated with CPAP therapy for OSA.
- Recurrent PTX in this patient was strongly associated with CPAP initiation, leading to its permanent discontinuation.
Implications:
- Clinicians should be aware of the rare but serious risk of PTX with CPAP use in OSA patients.
- Implementing lung-protective ventilation strategies and optimizing positive airway pressures may mitigate the risk of pulmonary barotrauma during CPAP therapy.
Related Concept Videos
Pneumothorax-II
Clinical Manifestations:
Sleep Apnea
The condition is more prevalent among...
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Other Pulmonary Disorders
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Acute Respiratory Failure-III

