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Updated: Nov 19, 2025

Determining Viral Disinfection Efficacy of Hot Water Laundering
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Inactivating SARS-CoV-2 by electrochemical oxidation.

Yunchuan Tu1,2, Wei Tang3, Liang Yu1,2

  • 1State Key Laboratory of Catalysis, Collaborative Innovation Center of Chemistry for Energy Materials, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

Science Bulletin
|February 1, 2021
PubMed
Summary

An eco-friendly electrochemical method rapidly inactivates SARS-CoV-2 using nickel oxide hydroxide. This sustainable approach effectively disinfects virus-laden aerosols and wastewater, offering a safer alternative to hazardous chemicals.

Keywords:
Electrochemical oxidationReactive oxygen speciesReceptor binding domainSARS-CoV-2

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Area of Science:

  • Environmental Science
  • Electrochemistry
  • Virology

Background:

  • Current SARS-CoV-2 disinfection methods utilize hazardous chemicals.
  • Effective inactivation of SARS-CoV-2 is crucial for preventing disease transmission.

Purpose of the Study:

  • To develop an eco-friendly and efficient electrochemical strategy for SARS-CoV-2 inactivation.
  • To investigate the mechanism of virus inactivation using *in-situ* formed nickel oxide hydroxide.

Main Methods:

  • Electrochemical inactivation using *in-situ* nickel oxide hydroxide anode and sodium carbonate electrolyte.
  • Mass spectrometry and theoretical calculations to elucidate the inactivation mechanism.

Main Results:

  • Achieved 95% SARS-CoV-2 inactivation in 30 seconds and 99.99% in 5 minutes at 5V.
  • Identified reactive oxygen species as the key agents causing peptide bond cleavage in the spike glycoprotein.
  • Demonstrated a sustainable and highly efficient disinfection process.

Conclusions:

  • The electrochemical strategy offers a sustainable and effective method for SARS-CoV-2 disinfection.
  • This approach can be applied to decontaminate viruliferous aerosols and wastewater.
  • Provides a safer alternative to conventional hazardous disinfectants.