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Updated: Aug 18, 2026

Chronic Salmonella Infected Mouse Model
Published on: May 31, 2010
Extensively drug-resistant Salmonella Typhi in a patient returning from Pakistan, complicated by relapse with
Maria A Caravedo1, Abhimanyu Kaura1, David Reynoso1
1Department of Infectious Diseases, University of Texas Medical Branch, Galveston TX, USA.
Abstract:
In developing countries, typhoid fever is a common cause of febrile illness accompanied by abdominal pain and weakness. It is caused by Salmonella enterica serovar Typhi. Humans are the only known reservoir of infection, and typhoid fever is common in regions where access to clean water and sanitation is limited. The antimicrobials of choice for a case of typhoid fever acquired outside Pakistan are third generation cephalosporins. Lately, cases of extensively drug-resistant (XDR) Salmonella Typhi have been reported in people with a travel history to Pakistan. We present a case of XDR typhoid fever which relapsed after treatment with meropenem.
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