Related Experiment Video

Updated: Nov 19, 2025

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

625

Aortic thrombosis in COVID-19

Helena Wickham1, Jerry C H Tam1, Xin Hui S Chan1,2

  • 1Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, UK.

Clinical Infection in Practice
|February 1, 2021
PubMed

Insights

Severe COVID-19 can cause arterial thrombosis, not just venous thrombo-embolism. This case highlights aortic and popliteal artery clots in a COVID-19 patient, emphasizing the need for further research into COVID-19-related clotting disorders.

Area of Science:

  • Cardiovascular Medicine
  • Infectious Diseases
  • Hematology

Background:

  • Venous thrombo-embolism is a recognized complication of severe COVID-19.
  • Arterial thrombosis is less recognized but increasingly reported in COVID-19 patients, often associated with myocardial infarction and stroke.

Observation:

  • A 63-year-old male COVID-19 patient presented with acute limb ischemia (pale, cold foot, absent pulse).
  • CT angiography revealed a large thrombus in the lower thoracic aorta and bilateral popliteal artery occlusion.
  • The aortic thrombus was a new finding compared to a prior CT pulmonary angiogram.

Findings:

  • This case demonstrates a rare instance of extensive arterial thrombosis (aortic and popliteal) in the context of COVID-19.
  • The patient was successfully treated with low molecular weight heparin (LMWH).

Implications:

  • This case underscores the diverse thrombotic complications of COVID-19, extending beyond venous events.
  • There is an urgent need for pathophysiological research and clinical trials to guide thromboprophylaxis strategies in COVID-19.
  • Understanding COVID-19's impact on arterial thrombosis is crucial for patient management and preventing severe outcomes.
Abstract

More Related Videos

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat04:30

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat

Published on: February 4, 2021

3.6K
Particle Image Velocimetry Investigation of Hemodynamics via Aortic Phantom06:26

Particle Image Velocimetry Investigation of Hemodynamics via Aortic Phantom

Published on: February 25, 2022

4.7K

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
86
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
189
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
186
Thoracic Aorta01:15

Thoracic Aorta

The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
1.1K
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
173
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
134