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Updated: Nov 19, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Acute haemorrhagic leukoencephalitis (Hurst disease) in severe COVID- 19 infection
Ala Haqiqi1, Theophilus Luke Samuels1, Fiona Jillian Lamb1
1Department of Critical Care Medicine, East Surrey Hospital, Surrey and Sussex Healthcare NHS Trust, Redhill, United Kingdom.
Abstract:
Coronavirus Disease 2019 (COVID-19) is well documented as a cause of respiratory tract infection. Increasingly, multi-systemic effects, including COVID-19-related neurologic features, are being reported. Here we report, what we believe to be, the first reported case of acute haemorrhagic leukoencephalitis (AHLE) with presence of oligoclonal bands in the cerebrospinal fluid. AHLE is a rare fulminant demyelinating disease, associated with severe COVID-19 infection.
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