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Cardiopulmonary function in long-term survivors of childhood Hodgkin's lymphoma: a pilot study
R P Kadota1, E O Burgert, D J Driscoll
1Section Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN 55905.
Mayo Clinic Proceedings
|April 1, 1988
Abstract:
Twelve patients who had received mantle radiotherapy for Hodgkin's lymphoma during childhood underwent cardiopulmonary testing 7 years or more after the initial diagnosis and treatment. All but one patient had been asymptomatic. Results of echocardiography, pulmonary function tests, or exercise studies were abnormal in 9 of the 12 patients. Long-term follow-up of cardiopulmonary function will be important to determine the ultimate significance of these abnormalities. These potential complications must be considered in planning prospective therapeutic studies in children with Hodgkin's disease.