Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anatomy of the Eyeball01:20

Anatomy of the Eyeball

8.8K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
8.8K
Glaucoma: Overview01:25

Glaucoma: Overview

1.1K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.1K
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

4.1K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
4.1K
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

2.8K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advances in Polypoidal Choroidal Vasculopathy (PCV) Management: Emerging Evidence for Faricimab and Aflibercept 8 mg.

Ophthalmology and therapy·2026
Same author

Aflibercept With vs Without Reduced-Fluence Photodynamic Therapy for Polypoidal Choroidal Vasculopathy: Optical Coherence Tomography Angiographic changes from a randomized clinical trial.

American journal of ophthalmology·2026
Same author

Drusenoid macular dystrophies in Singaporean Chinese: first report of Doyne honeycomb retinal dystrophy and late-onset retinal degeneration from Southeast Asia.

Ophthalmic genetics·2026
Same author

Clinical characteristics and progression rates of geographic atrophy in an Asian population from Singapore.

Eye (London, England)·2026
Same author

De novo and inherited dominant variants in U4 and U6 snRNA genes cause retinitis pigmentosa.

Nature genetics·2026
Same author

Cuticular drusen in Asian neovascular age-related macular degeneration: Clinical features and polypoidal choroidal vasculopathy association.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2025
Same journal

Tanshinone IIA Inhibits Choroidal Neovascularization and Restores Outer Blood-Retinal Barrier Function in Vldlr Knockout Mice.

Experimental eye research·2026
Same journal

Understanding the Ocular Accumulation of Mefuparib and its N-dealkylation metabolite: Pharmacokinetics, Melanin Affinity, and Cellular Disposition.

Experimental eye research·2026
Same journal

Mitochondrial Dysfunction and Diabetic Retinopathy: Research Progress from Pathogenic Mechanisms to Therapeutic Targets.

Experimental eye research·2026
Same journal

Middle-wavelength green ambient light attenuates lens-induced myopia progression and is associated with suppression of the Wnt/β-catenin signaling pathway in guinea pigs.

Experimental eye research·2026
Same journal

Experimental Corneal Alkali Burn Models: Methodological Standards, Biological Outcomes, and Translational Gaps.

Experimental eye research·2026
Same journal

Subretinal injection in the USH1CR31* pig model leads to chorioretinal atrophy that limits evaluation of efficacy of an AAV-mediated gene therapy.

Experimental eye research·2026
See all related articles

Related Experiment Video

Updated: Nov 19, 2025

Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry
05:15

Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry

Published on: October 20, 2019

9.0K

Inlays and the cornea.

Beau J Fenner1, Aline Silveira Moriyama2, Jodhbir S Mehta3

  • 1Singapore National Eye Centre, Singapore; Singapore Eye Research Institute, Singapore; Ophthalmology and Visual Sciences Academic Clinical Programme, SingHealth Duke-NUS Academic Medical Centre, Duke-NUS Graduate Medical School, Singapore.

Experimental Eye Research
|February 1, 2021
PubMed
Summary
This summary is machine-generated.

Presbyopia affects many aging adults seeking vision correction. This review examines corneal inlays, a surgical option to improve near vision and reduce spectacle dependence, discussing current and future technologies.

Keywords:
CorneaCorneal hazeFlexivueInlayKAMRAKeratophakiaKeratorefractive surgeryLASIKPresbyopiaRaindropSMILE

More Related Videos

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

12.9K
A Simplified Technique for In situ Excision of Cornea and Evisceration of Retinal Tissue from Human Ocular Globe
14:58

A Simplified Technique for In situ Excision of Cornea and Evisceration of Retinal Tissue from Human Ocular Globe

Published on: June 12, 2012

21.5K

Related Experiment Videos

Last Updated: Nov 19, 2025

Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry
05:15

Isolation of Intact Eyeball to Obtain Integral Ocular Surface Tissue for Histological Examination and Immunohistochemistry

Published on: October 20, 2019

9.0K
Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application
11:49

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Published on: March 8, 2019

12.9K
A Simplified Technique for In situ Excision of Cornea and Evisceration of Retinal Tissue from Human Ocular Globe
14:58

A Simplified Technique for In situ Excision of Cornea and Evisceration of Retinal Tissue from Human Ocular Globe

Published on: June 12, 2012

21.5K

Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Presbyopia is a common age-related condition impacting near vision.
  • An aging global population increases demand for spectacle-free vision correction solutions.
  • Corneal inlays are a surgical approach to address presbyopia.

Purpose of the Study:

  • To review historical and current corneal inlay technologies for presbyopia correction.
  • To critically evaluate the efficacy and complications of existing presbyopia-correcting corneal inlays.
  • To explore future directions and emerging technologies in corneal inlay treatments.

Main Methods:

  • Literature review of historical and current corneal inlay surgical approaches.
  • Critical appraisal of clinical data on presbyopia-correcting corneal inlays.
  • Analysis of emerging corneal inlay technologies and their potential.

Main Results:

  • Corneal inlays offer a method to enhance near vision by modifying corneal refractive properties.
  • Current inlays have shown varying degrees of success and associated complications.
  • Future technologies aim to improve outcomes and address limitations of existing inlays.

Conclusions:

  • Corneal inlays represent a significant area of research for presbyopia treatment.
  • Ongoing innovation in corneal inlay technology holds promise for improved spectacle-free vision.
  • Further research is needed to optimize inlay performance and patient satisfaction.