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Orbital exenteration: an updated review with perspectives.

Arnaud Martel1, Stephanie Baillif2, Sacha Nahon-Esteve1

  • 1Université Côte d'Azur, Ophthalmology department, Centre Hospitalier Universitaire de Nice, Nice, France.

Survey of Ophthalmology
|February 1, 2021
PubMed
Summary

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Orbital exenteration, a major surgery for eye cancers, is being re-evaluated. Emerging eye-sparing techniques offer alternatives, prompting a shift in treatment paradigms for orbital malignancies.

Area of Science:

  • Ophthalmology
  • Oncology
  • Surgical Oncology

Background:

  • Orbital exenteration is a radical surgery for advanced periocular and orbital tumors.
  • Historically, it was the primary treatment for these conditions.
  • Recent focus has shifted to minimizing surgical morbidity and improving cosmetic outcomes.

Purpose of the Study:

  • To review current data on orbital exenteration.
  • To discuss evolving treatment strategies for orbital malignancies.
  • To highlight the emergence of eye-sparing approaches.

Main Methods:

  • Review of epidemiological data.
  • Analysis of surgical techniques (ablative and reconstructive).
  • Evaluation of outcomes, complications, and controversies.
Keywords:
Eye-sparing surgeryOrbital exenterationOrbital reconstructionOrbital socketOverall survival

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Main Results:

  • Orbital exenteration remains a treatment option for specific orbital tumors.
  • Advances have reduced perioperative morbidity and improved prosthetics.
  • Questions persist regarding its impact on overall survival.

Conclusions:

  • A paradigm shift towards eye-sparing strategies is occurring.
  • Conservative surgery, potentially with adjuvant therapies, is gaining traction.
  • Further research is needed to compare survival outcomes between exenteration and newer methods.