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Related Experiment Video

Updated: Nov 19, 2025

An “All-laser” Endothelial Transplant
09:59

An “All-laser” Endothelial Transplant

Published on: July 6, 2015

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Laser-assisted corneal transplantation surgery.

Rashmi Deshmukh1, Louis J Stevenson2, Rasik B Vajpayee3

  • 1Division of Ophthalmology and Visual Sciences, Eye ENT Centre, Queens Medical Centre, University of Nottingham, UK.

Survey of Ophthalmology
|February 1, 2021
PubMed
Summary

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Articles linked to this work by shared authors, journal, and citation graph.

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Same author

Comparison of visual outcomes of phakic intraocular lens implantation in keratoconus and normal eyes.

International ophthalmology·2026
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Progressive inferior keratoconus in a patient misdiagnosed as pellucid marginal corneal degeneration.

BMJ case reports·2026
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Oxidative Stress in Keratoconus Is Evident in Tear Fluid and Stromal Cells and Alleviated in Cell Culture by Sulforaphane.

Investigative ophthalmology & visual science·2026
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Whole-exome sequencing for identification of genetic changes in adult-onset posterior polar cataract.

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Corneal transplantation triple procedures.

Survey of ophthalmology·2026
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Oxidative-stress related increase in keratoconus tear MDA and GPX3 while NRF2-antioxidant functions decrease in stromal cells.

bioRxiv : the preprint server for biology·2025

Laser-assisted keratoplasty offers improved precision and consistency in corneal transplants compared to manual methods. While enhancing tissue tailoring, challenges like cost and technical expertise remain for this advanced surgical technique.

Area of Science:

  • Ophthalmology
  • Surgical Technology
  • Biomedical Engineering

Background:

  • Corneal transplant outcomes are significantly influenced by surgeon skill and manual technique limitations.
  • Manual keratoplasty presents challenges in donor tissue and recipient bed preparation, impacting visual predictability.
  • Advancements in surgical techniques are crucial for improving corneal transplant consistency and patient outcomes.

Purpose of the Study:

  • To review laser-assisted keratoplasty techniques for corneal transplantation.
  • To evaluate the methods, precision, and efficacy of laser applications in various corneal conditions.
  • To compare laser-assisted approaches with traditional manual keratoplasty.

Main Methods:

  • Discussion of various laser platforms used in keratoplasty.
Keywords:
DALKExcimer laserFemtosecond laserKeratoplastyLamellar keratoplastyLaserPenetrating keratoplasty DSAEKPicosecond laserQ-switched laser

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  • Analysis of laser-assisted tissue preparation for donor grafts and recipient beds.
  • Review of studies comparing laser techniques to manual methods.

    • Main Results:

    • Laser-assisted keratoplasty demonstrates enhanced repeatability and consistency.
    • Lasers allow precise control over transplant tissue thickness and shape, tailored to patient needs.
    • Improved predictability of visual outcomes is associated with laser techniques.

    Conclusions:

    • Laser-assisted keratoplasty offers significant advantages in precision and customization over manual techniques.
    • Widespread adoption faces challenges related to cost-effectiveness and the need for specialized training.
    • Further research and technological integration are key to optimizing laser use in corneal surgery.